Memorial Drive once was the busiest road in Houston during the 1960s prior to the opening of the Katy Freeway, but the road was removed from the freeway plan by the early 1950s and the Holiday Inn opened in 1969 (according to Harris County Appraisal District), within months of Katy Freeway opening. As a result, the hotel (already only one way to access the front of the hotel) was left with terrible access points no matter the access.
The hotel, referred to the "Civic Center" Holiday Inn or the "Memorial Plaza" Holiday Inn (sources vary), had 13 floors (likely labeled "ground" and floors one through 12), and less than 300 rooms1. It was also operated directly by Holiday Inns of America Inc. itself rather than being a franchised operation. Details are unavailable if it changed hands before it closed permanently in 1986, and by 1989 it was already considered to be converted to housing for the elderly, though renovation and reopening plans fell through.2
In 1998, the property reopened as 2100 Memorial, and was at some point repainted burgundy from beige. The flooding and subsequent fire control damage from Hurricane Harvey nearly closed 2100 Memorial until courts ordered the building to stay open and make repairs. Pictures taken in October 2018 by the author.
1. Sources vary on the rooms. The 1970 Hotel & Motel Red Book says 297 but an article in the Houston Post reported 271.
2. Various articles found through NewsBank.