This (14255 Northwest Freeway) opened as Homestead Village in February 1994, a chain of extended-stay efficiency apartment hotels (not to be confused with Homestead Village Apartments at 9700 Homestead). In January 2001, it and others were sold to Accor, which converted them to Studio 6, Motel 6's new extended-stay hotel brand (it's worth noting the Studio 6 logo was much more colorful and interesting than it was prior to the early 2010s; you can see the hotel sign as it looked in 2005 from AARoads here). It changed signage in 2014. While "Studio 6 Houston, TX - Northwest Hwy 290" had a long run, it closed in 2022 and was converted into apartments along with two other Studio 6 properties and a Wyndham hotel.
The interesting thing to note is that at one time in the 2010s Studio 6 did some renovations, updating fixtures like cabinets and the sinks, and these were carried over to the apartment complex.
As an apartment complex, it appears that the main Northwest Freeway access is exit-only and that the main entrance is off of Rothway Street.